Do not take more or less of it than your doctor ordered.

Dosing

The dose of cabergoline will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of cabergoline. If your dose is different, do not change it unless your doctor tells you to do so.

• For oral dosage form (tablets):
  • For disorders of high prolactin levels or pituitary tumors:
    • Adults 0.25 mg two times a week. Dose may be increased every four weeks as needed, according to body prolactin levels, up to 1 mg two times a week.
    • Children Use and dose must be determined by the doctor.

Missed dose

If you miss a dose of this medicine, take it as soon as possible within 1 or 2 days. However, if it is almost time for your next dose, check with your doctor to see if you can double your dose.

Storage

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cabergoline, the following should be considered:

Allergies Tell your doctor if you have ever had any unusual or allergic reaction to cabergoline or other ergot alkaloid medicines. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy Cabergoline has not been shown to cause birth defects or other problems in humans. However, studies in animals have shown that cabergoline causes a decrease in successful pregnancies and other problems. This is because prolactin works differently in animal pregnancies than it does in human pregnancies. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding It is not known whether cabergoline passes into the breast milk. Cabergoline should not be used by breast-feeding women or women planning to breast-feed within a short period of time. Reducing the amount of available prolactin is likely to stop the release of breast milk in breast-feeding women.

Children Studies of this medicine have been done only in adult patients, and there is no specific information comparing use of cabergoline in children with use in other age groups.

Older adults Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of cabergoline in the elderly with use in other age groups.

Other medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking cabergoline, it is especially important that your health care professional know if you are taking any of the following:

• Antipsychotic medicines (medicines for mental illness) or
• Metoclopramide (e.g., Reglan) Cabergoline may stop these medicines from working properly and require a change in dose for these medicines

• High blood pressure, untreated or
• High blood pressure of pregnancy (or history of) Cabergoline usually decreases blood pressure but at times it may increase blood pressure and worsen these conditions

• Liver disease, mild to severe Cabergoline may worsen this condition; a lower dose of cabergoline may be required