Do not use almotriptan for a headache that is different from your usual migraines. Instead, check with your doctor.

To relieve your migraine as soon as possible, use almotriptan as soon as the headache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using almotriptan. Using almotriptan during the aura probably will not prevent the headache from occurring. However, even if you do not use almotriptan until your migraine has been present for several hours, the medicine will still work.

Lying down in a quiet, dark room for a while after you use this medicine may help relieve your migraine.

If you feel much better after a dose of almotriptan, but your headache comes back or gets worse after 2 or more hours, you may use one additional dose of almotriptan.

Your doctor may direct you to take another medicine to help prevent headaches. It is important that you follow your doctor's directions, even if your headaches continue to occur. Headache-preventing medicines may take several weeks to start working. Even after they do start working, your headaches may not go away completely. However, your headaches should occur less often, and they should be less severe and easier to relieve. This can reduce the amount of almotriptan or pain relievers that you need. If you do not notice any improvement after several weeks of headache-preventing treatment, check with your doctor.

Dosing

The dose of almotriptan will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of almotriptan. If your dose is different, do not change it unless your doctor tells you to do so.

• For oral dosage form (tablets):
  • For migraine headaches:
    • Adults 6.25 or 12.5 milligrams (mg) as a single dose. If the migraine comes back after being relieved, another dose be taken two hours or more after the first dose. Do not take more than 2 doses in any twenty-four-hour period.
    • Children Use and dose must be determined by your doctor.

Storage

To store this medicine:

• Keep out of the reach of children since overdose is especially dangerous in children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For almotriptan, the following should be considered:

Allergies Tell your doctor if you have ever had any unusual or allergic reaction to almotriptan. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy Almotriptan has not been studied in pregnant women. However, in some animal studies, almotriptan caused harmful effects to the fetus. These unwanted effects usually occurred when almotriptan was given in amounts that were large enough to cause harmful effects in the mother.

Breast-feeding It is not known whether almotriptan passes into human breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

Children Studies on this medicine have been done only in patients 18 years of age and older, and there is no specific information comparing use of almotriptan in children with use in other age groups.

Older adults Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of almotriptan in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Other medicines Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, especially other prescription medicine for migraine headaches, or if you smoke tobacco.

• Angina (chest pain) or
• Heart or blood vessel disease or
• High blood pressure or
• Kidney disease or
• Liver disease or
• Stroke (history of) The chance of side effects may be increased. Heart or blood vessel disease and high blood pressure sometimes do not cause any symptoms, so some people do not know that they have these problems. Before deciding whether you should use almotriptan, your doctor may need to do some tests to make sure that you do not have any of these conditions.